常規治療栢金遜症主要針對症狀的改善，而未有提供對腦部黑質體神經的保護， 黑質神經細胞持續死亡導致病情惡化。事實上，許多天然成分與傳統療法相結合可能具有互補作用。
這裏我們簡單探討一下這個題目。
酪氨酸和苯丙氨酸是多巴胺的氨基酸前體。
維他命B6、鋅和腎上腺激素DHEA已被證明可以增加大腦中的多巴胺形成。
刺毛黧豆 Mucuna pruriens(Kapikachhu)
這種來自印度的草本含有高濃度的天然L-DOPA和各種其他神經活性化合物。
CBD油
我們的身體和大腦通過分泌大麻素與受體結合，形成控制睡眠、食慾、情緒和很多其他作用。這些大麻素受體在基底神經節中數量特別多。研究人員認為， 補充天然大麻素與大腦受體結合，有助改善柏金遜症或幫助緩解症狀。
咖啡
多項研究發現飲用大量咖啡的人較少機會患上栢金遜症 。綠咖啡豆提取物含有比泡製咖啡更多的活性抗氧化劑， 或有助預防這種疾病。
另外， 咖啡所含的咖啡因很容易穿過血腦屏障並阻斷粘附受體，一些有趣的研究表明，咖啡因本身可能也是一種有效的抗柏金遜症藥物。
輔酶Q10
我們已知柏金遜症患者的血漿和血小板CoQ10水平較低， 補充輔酶q10或有助改善病情。
吡咯喹啉醌(PQQ)
吡咯喹啉醌(PQQ)是一種高生物活性化合物，廣泛存在於各種細胞類型中，研究人員認為提高PQQ水平可能會改善線粒體功能，抑制氧化作用，並支持神經系統健康。
肌酸
一些動物研究顯示，肌酸因其“促線粒體”作用，可有效預防或減緩栢金遜症的惡化 。肌酸對細胞能量管理至關重要。肌酸缺乏與神經損傷也有關係。
Omega-3脂肪酸
挪威的研究人員提出了令人信服的證據，證明柏金遜症患者體內缺乏 omega-3脂肪酸。
維他命 D
柏金遜症患者血液維他命D水平較低， 適量補充或有預防作用 。
綠茶
綠茶及其活性化合物兒茶素（EGCG） 或可作為預防柏金遜症的神經保護劑， 綠茶飲用量的增加與栢金遜症發病率降低有關。
薑黃素
薑黃素是香料黃薑的衍生物，通過其對體內NF-κB系統的有效調節，是一種天然的炎症抑製劑。 有研究發現薑黃素能發揮顯著的神經保護作用。
益生菌
補充益生菌顯著改善便秘問題，並減少腹脹和腹痛的發生率， 這些都是柏金遜症患者常見的腸胃問題。
Conventional treatment of Parkinson's disease relies heavily on targeting amelioration of symptoms, without providing neuroprotection against continual cell death in the substantia nigra. On the other hand, a variety of natural ingredients have been shown to support neuronal health and promote mitochondrial function in a variety of ways. Many natural ingredients may have a complementary effect in combination with conventional therapies.
Tyrosine and phenylalanine are amino acid precursors to dopamine. Vitamin B6, zinc, and the adrenal hormone DHEA also have been shown to increase dopamine formation in the brain.
Mucuna pruriens (Kapikachhu) is a vine whose seeds contain a high concentration of naturally occurring L-DOPA and a variety of other psychoactive compounds. Compounds in Mucuna seeds mimick the action of carbidopa and complement the action L-DOPA in the central nervous system.
CBD oil
Our bodies make natural cannabinoids that control sleep, appetite, mood and other processes by binding to receptors throughout the body and brain. These receptors are found in particularly high numbers in the basal ganglia, a circuit of brain cells that controls movement and is affected in Parkinson’s. Because the cannabinoids in hemp bind to the receptors in our body and brain, researchers believe that they could bind to brain receptors to modify the course of PD or help ease symptoms of disease.
Coffee Consumption
Several epidemiological studies have found that those who consume large amounts of coffee are much less likely to develop Parkinson's disease. Green coffee extract contains more of the active antioxidant compounds than brewed coffee, and may be a promising option for Parkinson's disease patients.
Intriguing research suggests that caffeine itself may be a potent anti-Parkinson agent. Upon ingestion, caffeine readily crosses the blood-brain barrier and blocks adenosine receptors, an effect responsible for many of its pharmacologic actions
CoQ10
Plasma and platelet levels of CoQ10 are known to be low in patients with Parkinson's disease, suggesting a systemic deficiency state.
Pyrroloquinoline Quinone (PQQ)
Pyrroloquinoline quinone, or PQQ, is a highly bioactive compound present in a vast range of cell types, and research suggests boosting PQQ levels may improve mitochondrial function, inhibit oxidative stress, and support neurological health.
Creatine
Creatine is vital to cellular energy management. Creatine deficiency is associated with neurological damage. Several animal studies have shown creatine, because of its "pro-mitochondrial" effect, to be effective in preventing or slowing the progression of Parkinson's disease
Omega-3 Fatty Acids
Researchers in Norway have presented convincing evidence of a systematic omega-3 deficit in Parkinson's disease,
Vitamin D
Several studies have shown that higher levels of vitamin D protect against the onset of Parkinson's disease symptoms. Also, that patients diagnosed with Parkinson's have lower serum vitamin D levels than those without the disease.
Green Tea
Increased tea consumption is correlated with reduced incidence of Parkinson's disease. There is tremendous scientific interest in green tea and its active compound Epigallocatechin gallate (EGCG) as a neuroprotectant in Parkinson's disease
Curcumin
Curcumin, a derivative of the spices turmeric, through its potent modulation of the NF-kappa B system is a natural inhibitor of inflammation. It prevents chemically induced changes in lab models of Parkinson's disease and exerts significant neuroprotection
Resveratrol
Scientists interested in protecting brain tissue and enhancing the quality of life in aging individuals have directed their attention towards resveratrol.
Probiotics
In a recent clinical trial, forty Parkinson's patients complaining of constipation were treated with probiotics for five weeks. Probiotic therapy significantly increased the number of normal stools as well as reduced the incidence of bloating and abdominal pain.
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