Wednesday, April 01, 2020

NAC對病毒的影響 NAC’s Effect on Viruses

洋蔥中發現的其中一種營養物質NAC可能有助舒緩病毒感染的症狀。

自1960年代以來,在洋蔥中大量發現的抗氧化劑n-乙酰半胱氨酸(NAC)作為某些毒藥的解毒劑和粘液稀薄物質而廣受歡迎。

現在,隨著COVID-19的迅速傳播(潛伏期更長,死亡率也比流感高),您可能想知道特定的營養素是否可以幫助保護您和您所愛的人。近來普遍提到的一種補品就是NAC。

NAC對冠狀病毒有效嗎?
未針對COVID-19進行測試
NAC對導致COVID-19的病毒的影響目前尚無研究。一項流感研究顯示,與安慰劑組相比,每天服用兩次每次600毫克(mg)NAC,連續六個月的一組“流感樣發作和臥床時間明顯減少”。

顯示減少表觀A / H1N1
NAC對另一種病毒性疾病A / H1N1的有效性研究的作者得出結論,長期服用NAC不能預防感染,但確實可以減少“臨床上明顯的疾病”的發生。

NAC’s Effect on Viruses
A nutrient found in onions may reduce symptoms.

Since the 1960s, the antioxidant n-acetylcysteine (NAC), which is found abundantly in onions has known popularity as an antidote to certain poisons and as a mucus-thinning substance.

Now, with the rapid spread of COVID-19, which has both a longer incubation period and a higher mortality rate than influenza, you may wonder whether particular nutrients can help protect you and those you love. One supplement that is being mentioned is NAC.

Is NAC Effective Against Coronavirus?
Not Tested Against COVID-19
There is as yet no research on NAC’s effect on the virus that causes COVID-19. One flu study showed “significantly fewer influenza-like episodes and days of bed confinement” for a group that had taken 600 milligrams (mg) of NAC twice a day for six months, as opposed to a placebo group.

Shown to Reduce Apparent A/H1N1
Authors of research on NAC’s effectiveness against another viral illness, A/H1N1, concluded that long-term administration of NAC did not prevent infection, but it did reduce the incidence of “clinically apparent disease.”

Sources:
“Attenuation of influenza-like symptomatology and improvement of cell-mediated immunity with long-term N-acetylcysteine treatment” by S. De Flora et al., European Respiratory Journal, 7/97

“Coronavirus disease 2019 (COVID-19),” Examine.com, updated 3/19/20

“Medical and dietary uses of N-acetylcysteine” by S. Salamon et al., Antioxidants, 5/19

“Nutraceuticals have potential for boosting the type 1 interferon response to RNA viruses including influenza and coronavirus” by Mark F. McCarty and James J. DiNicolantonio, Progress in Cardiovascular Diseases, ncbi.nlm.nih.gov, 2/20

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